Email us: info@biovita.lt

Sysmex OSNA

Sysmex OSNA image

Sysmex OSNA

Accurate determination of the metastatic burden by analysing the entire lymph node

Request a price

More differentiated information – supporting better treatment decisions

Lymph node status is one of the most important prognostic factors in many cancers and a key criterion for surgical and therapeutic decisions. Analysing lymph node tissue reliably and accurately is therefore crucial for detecting metastases.

Routine practice in histopathology analyses only a minimal amount of tissue and therefore provides only limited information, which might not reflect the real metastatic burden.

OSNA – One Step Nucleic Acid Amplification – is an automated molecular diagnostic assay that analyses the entire lymph node tissue. The reaction is based on rapid nucleic acid amplification technology (RT-LAMP*) to quantify Cytokeratin 19 (CK19) mRNA expression. CK19 is an epithelial cell marker and is normally not present in lymph node tissue. The expression rate of CK19 mRNA correlates with the size of the metastatic foci. 

The OSNA advantages

Excellent diagnostic information

  • More accurate determination of the metastatic burden by analysing the entire lymph node
  • Standardised, objective assessment of the lymph node status

Confidence

  • Fast availability of results for optimal decision-making as to the right surgical/non-surgical approach
  • Confident staging as reliable basis for choosing therapy

Patient quality of life

  • Next therapy measures can start earlier
  • Reduced waiting time and less patient stress

OSNA in breast cancer

A whole-lymph node analysis, resulting in an accurate staging and supporting better treatment decisions.
https://www.sysmex-europe.com/products/osna-in-breast-cancer-4717.html

OSNA in colorectal cancer

A whole-lymph node analysis, resulting in an accurate staging and supporting better treatment decisions.
https://www.sysmex-europe.com/products/osna-in-colorectal-cancer-4722.html

OSNA in gastric cancer

Molecular whole-node analysis for fast and accurate node assessment, fully-informed results supporting innovative approaches to reduce surgical radicality and enhanced staging.
https://www.sysmex-europe.com/products/osna-in-gastric-cancer-4723.html

OSNA in gynaecological cancer

Whole-lymph node analysis for fast and accurate sentinel node assessment, fully informed intraoperative results and enhanced staging accuracy.
https://www.sysmex-europe.com/products/osna-in-gynaecological-cancer-4949.html

OSNA in lung cancer

Unlike histopathological methods, OSNA (one-step nucleic acid amplification) enables a fast, molecular whole-node analysis. It provides nodal staging and prognosis accuracy as well as an improved basis for personalised fully-informed treatment decisions in the most common subtypes of lung cancer.
https://www.sysmex-europe.com/products/osna-in-lung-cancer-4899.html

OSNA in prostate cancer

Accurate, molecular whole-node analysis for fast, fully-informed intraoperative results supporting innovative approaches to reduce surgical radicality and enhanced staging in men.
https://www.sysmex-europe.com/products/osna-in-prostate-cancer-4951.html